Pain Insensitivity, Congenital

SCOPE: A syndrome characterized by indifference to PAIN despite the ability to distinguish noxious from nonnoxious stimuli. Absent corneal reflexes and MENTAL RETARDATION may be associated. Familial forms with autosomal recessive and autosomal dominant patterns of inheritance have been described. (Adams et al., Principles of Neurology, 6th ed, p1343)


NOTE: congenital insensitivity to pain with anhidrosis = HSAN IV see NEUROPATHIES, HEREDITARY SENSORY AND AUTONOMIC; DF: PAIN INSENSITIVITY CONGEN


YEAR of ENTRY: 96; was ANALGESIA, CONGENITAL 1964-95 (Prov 1964-72); PAIN INSENSITIVITY, CONGENITAL was see ANALGESIA, CONGENITAL 1973-95


SEARCH NOTE: use PAIN INSENSITIVITY, CONGENITAL to search ANALGESIA, CONGENITAL 1966-95 (as Prov 1966-72)


See Related:
HEREDITARY SENSORY AND AUTONOMIC NEUROPATHIES


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