Adrian-publications

Journal Articles

A. W. R. Serohijos, D. Tsygankov, S. Liu, T. C. Elston, and N. V. Dokholyan, "Multiscale approaches for studying energy transduction in dynein" Phys. Chem. Chem. Phys., In press (2009)
S. Ramachandran, A. W. R. Serohijos, L. Xu, G. Meissner, and N. V. Dokholyan, "Ryanodine pore structure and function" Public Library of Science Computational Biology, In press (2009)
D. Tsygankov, A. W. R. Serohijos, N. V. Dokholyan, and T. C. Elston, "Kinetic models for the coordinated stepping of cytoplasmic dynein" *J. Chem. Phys.* 130: 025101 (2009) \|Article, pdf\|
L. He, A.A. Aleksandrov, A.W.R. Serohijos, T. Hegedus, L.A. Aleksandrov, L. Cui, N.V. Dokholyan, J.R. Riordan, “Multiple membrane-cytoplasmic domain contacts in CFTR mediate regulation of channel gating” J. Biol. Chem. 283: 26383-26390 (2008) \|Article, pdf\|
J. Hao, A.W.R. Serohijos*, G. Newton, G. Tassone, Z. Wang, D.C. Sgroi, N.V. Dokholyan, and J.P. Basilion, "Identification and rational redesign of peptide ligands to CRIP1, a novel biomarker for cancers" Public Library of Science Computational Biology 4: e1000138 (2008) [Equal contribution] \|Article, pdf\|
T. Hegedus, A.W.R. Serohijos, N.V. Dokholyan, L. He, J.R. Riordan, “Computational studies reveal phosphorylation dependent changes in the unstructured R domain of CFTR” J. Mol. Biol. 378: 1052-1063 (2008) \|Article, pdf\|
A.W.R. Serohijos, T. Hegedus, A.A. Aleksandrov, L. He, L. Cui, N.V. Dokholyan, J.R. Riordan, “Phenylalanine 508 forms interdomain contact in the CFTR structure crucial to folding and function” Proc. Natl. Acad. Sci. USA 105: 3256-3261 (2008) \|Article, pdf\|Supporting Information, pdf\|
A.W.R. Serohijos, T. Hegedust, J. Riordan, and N.V. Dokholyan, “Diminished self-chaperoning activity of the DF508 mutant CFTR results in protein misfolding” Public Library of Science Computational Biology 4: e1000008 (2008) [*Equal contribution] \|Article, pdf\|
Y. Chen, F. Ding, H. Nie, A.W.R. Serohijos*, S. Sharma, K.C. Wilcox, S. Yin, and N.V. Dokholyan, "Protein folding: then and now" Archives of Biochemistry and Biophysics* 468: 4-19 (2008) [*Equal contribution] \|Article, pdf\|
A.W.R. Serohijos, Y. Chen, F. Ding, T.C. Elston, and N.V. Dokholyan, “A new structural model reveals energy transduction in dynein” Proc. Natl. Acad. Sci. USA 103: 18540-18545 (2006) \|Article, pdf\|Supporting Information, pdf\| [Cited as Recommended Reading by Faculty of 1000 Biology: http://www.f1000biology.com/article/id/1052660/evaluation]

A. W. R. Serohijos, D. Tsygankov, S. Liu, T. C. Elston, and N. V. Dokholyan, "Multiscale approaches for studying energy transduction in dynein" Phys. Chem. Chem. Phys., In press (2009)
S. Ramachandran, A. W. R. Serohijos, L. Xu, G. Meissner, and N. V. Dokholyan, "Ryanodine pore structure and function" Public Library of Science Computational Biology, In press (2009)
D. Tsygankov, A. W. R. Serohijos, N. V. Dokholyan, and T. C. Elston, "Kinetic models for the coordinated stepping of cytoplasmic dynein" *J. Chem. Phys.* 130: 025101 (2009) \|Article, pdf\|
L. He, A.A. Aleksandrov, A.W.R. Serohijos, T. Hegedus, L.A. Aleksandrov, L. Cui, N.V. Dokholyan, J.R. Riordan, “Multiple membrane-cytoplasmic domain contacts in CFTR mediate regulation of channel gating” J. Biol. Chem. 283: 26383-26390 (2008) \|Article, pdf\|
J. Hao, A.W.R. Serohijos*, G. Newton, G. Tassone, Z. Wang, D.C. Sgroi, N.V. Dokholyan, and J.P. Basilion, "Identification and rational redesign of peptide ligands to CRIP1, a novel biomarker for cancers" Public Library of Science Computational Biology 4: e1000138 (2008) [Equal contribution] \|Article, pdf\|
T. Hegedus, A.W.R. Serohijos, N.V. Dokholyan, L. He, J.R. Riordan, “Computational studies reveal phosphorylation dependent changes in the unstructured R domain of CFTR” J. Mol. Biol. 378: 1052-1063 (2008) \|Article, pdf\|
A.W.R. Serohijos, T. Hegedus, A.A. Aleksandrov, L. He, L. Cui, N.V. Dokholyan, J.R. Riordan, “Phenylalanine 508 forms interdomain contact in the CFTR structure crucial to folding and function” Proc. Natl. Acad. Sci. USA 105: 3256-3261 (2008) \|Article, pdf\|Supporting Information, pdf\|
A.W.R. Serohijos, T. Hegedust, J. Riordan, and N.V. Dokholyan, “Diminished self-chaperoning activity of the DF508 mutant CFTR results in protein misfolding” Public Library of Science Computational Biology 4: e1000008 (2008) [*Equal contribution] \|Article, pdf\|
Y. Chen, F. Ding, H. Nie, A.W.R. Serohijos*, S. Sharma, K.C. Wilcox, S. Yin, and N.V. Dokholyan, "Protein folding: then and now" Archives of Biochemistry and Biophysics* 468: 4-19 (2008) [*Equal contribution] \|Article, pdf\|
A.W.R. Serohijos, Y. Chen, F. Ding, T.C. Elston, and N.V. Dokholyan, “A new structural model reveals energy transduction in dynein” Proc. Natl. Acad. Sci. USA 103: 18540-18545 (2006) \|Article, pdf\|Supporting Information, pdf\| [Cited as Recommended Reading by Faculty of 1000 Biology: http://www.f1000biology.com/article/id/1052660/evaluation]

2009	Biophysics Society Annual Meeting. "Phe508 forms an interdomain contact in CFTR crucial to folding and dynamics" (contributed talk) Boston, MA
2009	UNC Virtual Lung Consortium. "Modeling CFTR structure and etiology" (invited talk) Chapel Hill, NC
2009	International Conference on Biomolecular Engineering. "Applications of conformational sampling and sequence sampling in protein engineering--discrete molecular dynamics and Medusa molecular modeling tools" (contributed talk with Dr. Feng Ding of UNC-CH) Santa Barbara, CA
2009	International Conference on Biomolecular Engineering. "Identification and rational design of a ligand peptide to CRIP1, a novel cancer biomarker" (contributed poster) Santa Barbara, CA
2008	Quantitative Programs Recruitment Week, UNC School of Medicine. “Molecular etiology of cystic fibrosis.” (invited talk) Chapel Hill, NC
2008	Physics Dept. and Biology Dept., Ateneo de Manila University. “Physics meets biology: understanding living phenomena using physical techniques.” (invited talk) Quezon City, Philippines
2008	Centennial Lecture Series, University of the Philippines in the Visayas. “Physics meets biology: understanding living phenomena using physical techniques.” (invited talk) Cebu City, Philippines
2007	Polycystic Kidney Disease Group, UNC School of Medicine. “Modeling the structure and mechanism of cytoplasmic dynein.” (invited talk) Chapel Hill, NC
2006	Carolina Biophysics Symposium. “Modeling the structure and mechanism of cytoplasmic dynein.” (invited talk) Chapel Hill, NC
2006	Biophysics Society Discussions. “A new model reveals energy transduction in cytoplasmic dynein.” (contributed poster) Pacific Grove, CA
2006	Duke Systems Biology Symposium. “A new model reveals energy transduction in cytoplasmic dynein.” (contributed poster) Durham, NC
2006	UNC Biophysics Student Symposium. “Modeling the structure and mechanism of cytoplasmic dynein.” (invited talk) Chapel Hill, NC