76) Dillon PJ, Gregory SM, Tamburro K,
Sanders MK, Johnson GL, Raab-Traub N, Dittmer DP, Damania
B. Tousled-like Kinases Modulate Reactivation of
Gammaherpesviruses from Latency.
Cell Host Microbe. 2013 Feb 13;13(2):204-14. doi:
10.1016/j.chom.2012.12.005. (In press)
|
75) Roy D, Sin SH, Lucas AS, Venkataramanan
R, Wang L, Eason A, Chavakula V, Tamburro KM, Hilton IB,
Damania B, Dittmer DP. mTOR inhibitors block Kaposi
sarcoma growth by inhibiting essential autocrine growth
factors and tumor angiogenesis. Cancer Res. 2013 Feb 4.(In
press)
|
74) Horan KA, Hansen K, Jakobsen MR, Holm
CK, Søby S, Unterholzner L, Thompson M, West JA,
Iversen MB, Rasmussen SB, Ellermann-Eriksen S, Kurt-Jones
E, Landolfo S, Damania B, Melchjorsen J, Bowie AG,
Fitzgerald KA, Paludan SR. Proteasomal degradation of
herpes simplex virus capsids in macrophages releases DNA
to the cytosol for recognition by DNA sensors.J. Immunol.
2013 Mar 1;190(5):2311-9. doi: 10.4049/jimmunol.1202749.
|
73) Bhatt AP, Damania B. AKTivation of
PI3K/AKT/mTOR signaling pathway by KSHV. Front Immunol.
2012;3:401. doi: 10.3389/fimmu.2012.00401. Epub 2013 Jan
7.
|
72) Chen W, Sin SH, Wen KW, Damania B,
Dittmer DP. Hsp90 inhibitors are efficacious against
Kaposi Sarcoma by enhancing the degradation of the
essential viral gene LANA, of the viral co-receptor EphA2
as well as other client proteins.
PLoS Pathog. 2012 Nov;8(11):e1003048. doi:
10.1371/journal.ppat.1003048.
|
71) Jacobs SR, Gregory SM, West JA, Wollish
AC, Bennett CL, Blackbourn DJ, Heise MT, Damania B.
The viral interferon regulatory factors of kaposi's
sarcoma-associated herpesvirus differ in their inhibition
of interferon activation mediated by toll-like receptor 3.
J Virol. 2013 Jan;87(2):798-806. doi:
10.1128/JVI.01851-12. Epub 2012 Oct 31.
-J. Virology Spotlight Feature article
|
70) West JA, Gregory SM, Damania
B.Toll-like receptor sensing of human herpesvirus
infection. Front Cell Infect Microbiol. 2012;2:122. doi:
10.3389/fcimb.2012.00122.
|
69) Tamburro KM, Yang D, Poisson J,
Fedoriw Y, Roy D, Lucas A, Sin SH, Malouf N, Moylan V,
Damania B, Moll S, van der Horst C, Dittmer DP. Vironome
of Kaposi sarcoma associated herpesvirus-inflammatory
cytokine syndrome in an AIDS patient reveals co-infection
of human herpesvirus 8 and human herpesvirus 6A.Virology.
2012 Nov 10;433(1):220-5. doi:
10.1016/j.virol.2012.08.014.
|
68) Bhatt, AP., Jacobs,
SR., Freemerman, AJ, Makowski L, Rathmell, JC, Dittmer,
DP, and B. Damania. Dysregulation of fatty acid
synthesis and glycolysis in non-Hodgkin lymphoma. 2012.
Proceedings of the National Academy of Sciences (PNAS).
Jul 17;109(29):11818-23.
|
67) Damania B,
Blackbourn DJ. Innate barriers to viral infection. Future
Microbiol. 2012 Jul;7:815-22.
|
66) Lei Y, Wen H, Yu Y,
Taxman DJ, Zhang L, Widman DG, Swanson KV, Wen KW, Damania
B, Moore CB, Giguère PM, Siderovski DP, Hiscott J,
Razani B, Semenkovich CF, Chen X, Ting JP.
The Mitochondrial Proteins NLRX1 and TUFM Form a Complex
that Regulates Type I Interferon and Autophagy.Immunity.
2012. 36(6):933-46.
|
65) Jacobs SR, Damania
B. NLRs, inflammasomes, and viral infection. J
Leukoc Biol. 2012 May 10.
|
64) Dittmer DP, Richards
KL, Damania B. Treatment of kaposi sarcoma-associated
herpesvirus-associated cancers. Front Microbiol.
2012;3:141. Epub 2012 Apr 18.
|
63) Dittmer DP, Bhatt AP,
Damania B.Rapalogs in viral cancers. Expert Opin Investig
Drugs. 2012 Feb;21(2):135-8.
|
62) Gregory SM, Wang L,
West JA, Dittmer DP, Damania B. Latent Kaposi's
sarcoma-associated herpesvirus infection of monocytes
downregulates expression of adaptive immune response
costimulatory receptors and proinflammatory cytokines.
J Virol. 2012 Apr;86(7):3916-23. Epub 2012 Jan 25.
|
61) Dittmer DP, Bhatt AP,
Damania B.Rapalogs in viral cancers. Expert Opin Investig
Drugs. 2012 Feb;21(2):135-8. Epub 2012 Jan 4.
|
60) Gregory SM,
Damania B. Inhibition of the inflammasome response by a
viral protein that interacts with NLRs. Commun Integr
Biol. 2011 Jul;4(4):416-8.
|
59)
Guilluy C, Zhang Z, Bhende PM, Sharek L, Wang L,
Burridge K, Damania B. Latent
KSHV infection increases the vascular permeability of
human endothelial cells. Blood. 2011 Aug 31.
|
58) Roy D, Sin SH,
Damania B, Dittmer DP. Tumor
suppressor
genes FHIT and WWOX are deleted in primary effusion
lymphoma (PEL) cell lines. Blood. 2011 Aug 18;118(7):e32-9.
|
57) Gregory,SM, Davis,BK.,
West, JA., Taxman, D., Matsuzawa, S., Reed, J., Ting.
JP, and B. Damania. Discovery of a Viral NLR
Homolog that Inhibits the Inflammasome. Science.
2011.
This article was featured in:
-Da Silva, K. Editors’
Choice: Evasion through evolution. Nature Medicine 2011
-Sanchez, C. Research
Highlight: Viral immune evasion: NLR identity theft.
Nature Reviews Microbiology 2011
-Dempsey, L. Research
Highlight: Viral inflammasome inhibitor. Nature
Immunology 2011.
-Mueller, K. Editors’
Choice: Immune Evasion tactic. Science Signaling. 2011
-F1000 Biology
(F1000.com/8136972) and (F1000.com/8136972)
|
56) Ozgur S, Damania B,
Griffith J. The Kaposi's sarcoma-associated
herpesvirus ORF6 DNA binding protein forms long DNA-free
helical protein filaments. J Struct Biol. 2011
|
55)
West
JA, Gregory SM, Sivaraman V, Su L, Damania B. Activation
of Plasmacytoid Dendritic Cells by Kaposi's
Sarcoma-Associated Herpesvirus. J Virol. 2011.
85(2):895-904.
|
54) Bhende PM, Park SI, Lim
MS, Dittmer DP, Damania B. The dual PI3K/mTOR inhibitor,
NVP-BEZ235, is efficacious against follicular lymphoma.
Leukemia. 2010. 24(10):1781-4.
|
53) Moyo TK, Richards KL,
Damania B. Use of cidofovir for the treatment of
HIV-negative human herpes virus-8-associated primary
effusion lymphoma. Clin Adv Hematol Oncol. 2010.
(5):372-4.
|
| 52) Bhatt, AP, Bhende, PM,
Sin, SH, Roy, D, Dittmer, DP and B. Damania. Dual
inhibition
of
PI3K and mTOR inhibits autocrine and paracrine
proliferative loops in PI3K/Akt/mTOR-addicted lymphomas. Blood. 2010.
115(22):4455-63. |
| 51)
Wen,
K and B. Damania. HSP90 and HSP40/Erdj3 are
required for the expression and anti-apoptotic function
of KSHV K1. Oncogene. 2010. 29(24):3532-44. |
50) West JA, Damania
B. Kaposi's sarcoma-associated herpesvirus and
innate immunity.Future Virol. 2010 Mar 1;5(2):185-196.
|
49) Gregory SM,
Damania B. KSHV and the toll of innate
immune activation. Cell Cycle. 2009 Oct
15;8(20):3246-7.
|
48) González CM,
Wang L, Damania B. KSHV Encodes a Viral Deubiquitinase.
J Virol. 2009 Oct;83(19):10224-33.
|
47)
Wen
KW, Damania B. Kaposi sarcoma-associated herpesvirus
(KSHV): Molecular biology and oncogenesis. Cancer Lett.
2009.
|
46) Wen, KW, Dittmer, DP
and B. Damania. Disruption of LANA in rhesus
rhadinovirus generates a highly lytic recombinant virus. J
Virol. 2009 Oct;83(19):9786-802.
|
45) Gregory SM, West JA,
Dillon PJ, Hilscher C, Dittmer DP, Damania B.
Toll-like receptor signaling controls reactivation of
KSHV from latency. Proc Natl Acad Sci U S A. 2009 Jun
29.
This article was highlighted in Science
Signaling: L. Bryan Ray. For Whom the Toll-Like
Receptor Signals. Sci. Signal.,Vol. 2, Issue 80,
p. ec242
|
44) O'Hara AJ, Chugh
P, Wang L, Netto EM, Luz E, Harrington WJ, Dezube BJ,
Damania B, Dittmer DP. Pre-micro RNA signatures delineate
stages of endothelial cell transformation in Kaposi
sarcoma. PLoS Pathog. 2009 Apr;5(4). Website:
http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000389
|
| 43) O'Hara AJ, Wang L,
Dezube BJ, Harrington WJ Jr, Damania B, Dittmer
DP. Tumor suppressor micro RNAs are
underrepresented in primary effusion lymphoma and Kaposi
sarcoma. Blood.
2009 Feb 27. |
42)
Wang, L. and B. Damania. KSHV confers a cell
survival advantage to endothelial cells. Cancer
Research. 2008. 68(12):4640-8.
This article was highlighted in Nature
Reviews Cancer: Angiogenesis: Survival of the
Infected. Vol.8, page 569 (August 2008).
This article was also
featured in the August 2008 Signaling Gateway Highlights
section:
http://www.signaling-gateway.org/update/updates/200808/index.html
|
| 41)
Tomlinson, CC and B. Damania.A critical role for
endocytosis in the regulation of signaling by the KSHV
K1 protein. J. Virology. 2008. 82(13):6514-23. |
| 40)
West, J. and B. Damania. Upregulation of the TLR3
pathway by Kaposi's sarcoma-associated herpesvirus
during primary infection. J. Virology. 2008. 82(11):5440-9. |
39) Nun, T.K., Kroll
D.J.,Oberlies,N.H., Soejarto, DD, Case, RJ, Piskaut,
P.,Matainaho, T., Hilscher, C., Wang, L., Dittmer, DP.,
Gao, SJ and B. Damania. Development of a Novel, High
Throughput Assay to Screen Anti-Viral Drugs against
Kaposi’s Sarcoma-Associated Herpesvirus. Molecular Cancer
Therapeutics. 2007. Aug;6(8):2360-70.
|
38)
Mark, L. Spiller, Okroj, Chanas, Aitken, Wong,S.,
Damania,B., Blom,H and D. Blackbourn. Molecular
characterization of the Rhesus Rhadinovirus (RRV)
ORF4 gene and the RRV complement control protein (RCP)
it encodes. J Virol. 2007 Apr;81(8):4166-76.
|
37)
Hoon-Sin,S., Roy,D., Wang,L., Staudt M.R., Fakhari,FD.,
Patel,DD. Koon,H., Damania, B. and D.P. Dittmer.
Rapamycin is efficacious against primary effusion
lymphoma (PEL). Blood. 2007 Mar 1;109(5):2165-73.
|
36)
Damania
B. DNA tumor viruses and human cancer. Trends in
Microbiology. 2007.
|
35) Wang, L., Dittmer, D. P.,
Tomlinson, C.C., Fakhari, F.D. and B. Damania.
“Immortalization of primary endothelial cells by the K1
protein of Kaposi’s sarcoma-associated herpesvirus
(KSHV). 2006. Cancer Research. 66(7):3658-66.
|
34)
Bowser, B.S., Song, M.J., Sun, R., Morris, S. and B.
Damania. “Identification of Multiple Rta
Responsive Elements in the KSHV K1 promoter.”
2006. Virology. 348(2):309-27.
|
33)
Gonzalez, C.M., Wong, E.L., Bowser, B.S., Hong, G,
Kenney S. and B. Damania. Identification and
Characterization of the KSHV Orf49 Protein. 2006. J.
Virology. 80(6):3062-70.
|
| 32)
Wong, E.L. and B. Damania. Transcriptional
Regulation of the Kaposi’s Sarcoma-Associated
Herpesvirus K15 Gene. 2006. J. Virology;80 1385-1392. |
| 31)
Bilelo, J., Morgan, J. Damania, B., Lang, S, and RC
Desrosiers. A Genetic System for Rhesus Monkey
Rhadinovirus: Use of Recombinant Virus to Quantitate
Antibody-Mediated Neutralization. 2006. J.
Virology;80 1549-1562. |
30)
Hong, G., Kumar, P., Wang, L., Damania, B., Gulley,
M.L., Delecluse H-J., Polverini, P., and S. Kenney.
Epstein-Barr Virus Lytic Infection is Required for
Efficient Production of the Angiogenesis Factor VEGF in
Lymphoblastoid Cell Lines. J Virol. 2005
79(22):13984-92.
|
| 29) Wong, E.L. and B.
Damania. Linking KSHV to Human Cancer.2005.
Current Oncology Reports (5):349-356. |
| 28) Dittmer, D.P., Gonzalez
C.M., Vahrson, W., DeWire, S.M., and B. Damania.
“Whole-Genome Transcription Profiling of Rhesus Monkey
Rhadinovirus.” 2005. Journal of Virology 79: 8637-8650. |
| 27)
Cai, W., Lu, S., Zhang, Z., Gonzalez, C.M., Damania B.,
and B. Cullen. Kaposi’s sarcoma associated
herpesvirus expresses an array of novel viral microRNAs
in latently infected cells. 2005. Proc. Natl. Acad.
Sciences. 2005. 102(15):5570-5. |
| 26) DeWire, S. and B.
Damania. “The Latency-Associated Nuclear Antigen of
Rhesus Monkey Rhadinovirus (RRV) Inhibits Viral
Replication through Repression of Orf50/Rta
Transcriptional Activation.” J. Virol. 2005. 79;
3127-3138.
|
25) Payton ME, d'Offay JM,
Prado ME, Black DH, Damania B, White GL, Eberle R.
Comparative transmission of multiple herpesviruses and
simian virus 40 in a baboon breeding colony. Comp Med.
2004. 54(6):695-704.
|
24) Pagano, J.S. Blaser, M.
Buendia, M.A., Damania, B., Khalili, K. Raab-Traub, N.,
Roizman, B. Validation Of A Causal Relationship:
Criteria To Establish Etiology of Viral Cancers.
Seminars in Cancer Biology. Semin Cancer Biol. 2004.
14(6):453-71.
|
23) Damania,
B. Oncogenic Gammaherpesviruses: Comparison of
Viral Proteins involved in Tumorigenesis. Nature
Reviews Microbiology, 2004. Vol. 2, pp.656-668.
|
| 22) Damania, B. Modulation
of cell signaling pathways by Kaposi’s
Sarcoma-Associated Herpesvirus (KSHV/HHV-8). Cell
Biochemistry & Biophysics, 2004.Vol. 40, pp. 305-322
|
21)
Wang,
L., Wakisaka N., Tomlinson, C., DeWire S., Krall,
S., Pagano, J. and B. Damania. "The Kaposi’s
Sarcoma-Associated Herpesvirus (KSHV/HHV8) K1
Protein Induces Expression of Angiogenic and
Invasion Factors." Cancer Research.2004. 64.
pp.2774-2781.
|
20) Damania B., J. H. Jeong,
B. S. Bowser, S. M. DeWire and D. P. Dittmer. “A
Functional Comparison of Rta Transactivator Proteins of
Gamma-2 Herpesviruses.” J.Virol. 2004. 78. p.5491-5499.
|
| 19)
Tomlinson,
C.C.,
and B. Damania. The K1 Protein of Kaposi’s
Sarcoma-Associated Herpesvirus Activates the Akt
Signaling Pathway. J. Virol. 2004. 78 (4):
1918-27. |
18) O’Connor, C., Damania, B.
and Kedes, D.H. Capsid. De Novo Infection
with Rhesus Monkey Rhadinovirus Leads to the
Accumulation of Multiple Intranuclear Capsid Species
during Lytic Replication but Favors the Release of
Genome-Containing Virions. J Virol. 2003 Dec
15;77(24):13439-13447.
|
17) Yu,
X.K., O’Connor, C., Atanosov, I., Damania, B., Kedes,
D., and Z.H. Zhou. Three-Dimensional Structures of
the A, B, and C Capsids of Rhesus Monkey Rhadinovirus:
Insights into Gammaherpesvirus Capsid Assembly,
Maturation, and DNA Packaging. J Virol. 2003 Dec
15;77(24):13182-13193.
|
16)
DeWire,
S.M.,
Money, E.S., Krall, S.P., and B. Damania. Rhesus Monkey
Rhadinovirus (RRV): Construction of a RRV-GFP
Recombinant Virus and the Development of Assays to
Assess Viral Replication. 2003. Virology. 312 (1):
122-134.
|
15)
Bowser, B.S., DeWire, S. and B. Damania.
Transcriptional Regulation of the KSHV K1 viral gene of
Kaposi’s sarcoma-associated herpesvirus.
2002.Journal of Virology, 76 (24): 12574-12583.
|
| 14)
DeWire,
S.,
McVoy,, M., and B. Damania. Kinetics of Expression
of Rhesus Monkey Rhadinovirus (RRV) and the
Identification and Characterization of a polycistronic
transcript encoding the RRV Orf 50/Rta, RRV
R8 and R8.1 genes. 2002.Journal of Virology, 76(19):
9819-9831. |
13) Damania, B. and R.C.
Desrosiers. Oncogenic gamma-herpesviruses.
Philosophical Transactions of the Royal
Society.2001.
|
12)
Choi
JK,
Means R, Damania B., and J.U. Jung. Molecular piracy of
Kaposi’s sarcoma associated herpesvirus.2001. Cytokine
and Growth Factor Rev. 12(2-3):245-257.
|
11) Damania, B and J.U.
Jung. Comparative analysis of the transforming
mechanisms of Epstein-Barr virus, Kaposi's
sarcoma-associated herpesvirus, and Herpesvirus saimiri.
2000. Advances in Cancer Research, 80:51-82.
|
10)
Li,
M.,
Damania, B. Alvarez, X., Ogryko, G., Ozato, K.,
and J.U. Jung. The Kaposi sarcoma herpesvirus vIRF
gene inhibits histone acetyltransferases.
Molecular & Cellular Biology. 20(21):8254-63. 2000.
|
9) Lee, B.S., Damania, B.,
and J.U. Jung. The Kaposi's sarcoma-associated herpesvirus
K1 and Rhesus Monkey Rhadinovirus R1 proteins. EBV Report.
1999. Vol. 6 (5), pp. 123-125.
|
8)
Alexander,
L.,
Denekamp, L., Auerbach, M., Knappe, A., Damania, B. and
R.C. Desrosiers. Sequence analysis of Rhesus
Rhadinovirus Isolate H26-95.Journal of Virology, 2000 76
(8).
|
7) Damania, B. DeMaria,
M., Jung, J.U. and R.C. Desrosiers Activation of
lymphocyte signaling by the R1 protein of Rhesus monkey
rhadinovirus.Journal of Virology, 2000 (76)6.
|
6) Damania, B., Choi,
J.K. and Jung J.U. Gammaherpesviruses:
Transforming functions of the first open reading frames.
J. Virol. 1999.Journal of Virology, 2000. 76 (4).
|
| 5) Damania, B. Lee, H. and
Jung, J.U. Primate herpesviral oncogenes. Mol.
Cells, 1999. Vol. 9 (4), pp. 20-24. |
| 4) Damania B, Li M,
Choi JK, Alexander L, Jung JU, Desrosiers RC. Identification and
characterization of the R1 oncogene and its protein product
from the rhadinovirus of rhesus monkeys. J.
Virol., 1999. Vol. 73(6), pp. 5123-5133.
|
3) Damania B, Lieberman P,
Alwine JC. Simian virus 40 large T antigen stabilizes the
TATA-binding protein-TFIIA complex on the TATA element.
Mol Cell Biol. 1998 Jul;18(7):3926-35.
|
2) Damania B, Mital R,
Alwine JC. Simian virus 40 large T antigen interacts
with human TFIIB-related factor and small nuclear
RNA-activating protein complex for transcriptional
activation of TATA-containing polymerase III promoters.
Mol Cell Biol. 1998 Mar;18(3):1331-8.
|
1) Damania B, Alwine
JC. TAF-like function of SV40 large T antigen. Genes
Dev. 1996 Jun 1;10(11):1369-81.
|
