Clemmons Research Statement

 

Areas of Research Interest

Basic:

  • Mechanisms by which insulin-like growth factor binding proteins act to alter cellular replication and differentiation
  • Control of fibroblast and smooth muscle cell replication by IGF's, their binding proteins and related peptides
  • Structure and function analysis of insulin-like growth factor binding proteins
  • Role of IGF's in atherosclerosis, arthritis, and the response to injury
 

Clinical:

  • Interaction between growth hormone and nutritional status in controlling protein metabolism
  • Metabolic responses to IGF-I administration in humans
  • Use of IGF and IGFBP measurement to assess growth hormone and nutritional status

 

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