DITTMER LAB
PUBLICATIONS

D. Dittmer, C. Stoddart, R. Renne, V. Linquist-Stepps, C. Bare, J.M. McCune and D. Ganem, ”Experimental Transmission of Kaposi’s Sarcoma-Associated Herpesvirus (KSHV/HHV-8) to SCID-hu Thy/Liv Mice ”, J. Exp. Med. 190, 1857-1868 (1999)

J. Jeong, J. Papin and D. Dittmer “Differential Regulation of the overlapping Kaposi’s Sarcoma-associated Herpesvirus (KSHV/HHV-8) vGCR (orf74) and LANA (orf73) promoter”, J. Virology 75, 1798-1807 (2001)

F. Fakhari and D. Dittmer, “Charting latency genes by whole genome real-time quantitative RT-PCR in Kaposi’s Sarcoma-associated Herpesvirus (KSHV/HHV-8)”, J. Virology 76, 6213-6223 (2002)

J. Jeong, R. Hines-Boykin, JD. Ash and D. Dittmer “Kaposi’s sarcoma-associated Herpesvirus (KSHV) latent nuclear antigen (LANA/orf73) promoter shows B-lymphocyte and endothelial-specificity in transgenic mice”, J. Virology 76, 11024-11032 (2002)

R. Renne, D. Dittmer, D. Kedes, K. Smith, R. Desrosiers, P.A. Luciw, D. Ganem, ”Experimental Transmission of Kaposi’s Sarcoma-associated Herpesvirus (KSHV/HHV-8) to SIV-positive and SVI-negative Rhesus macaques”, J. Medical Primatology 33, 1-9 (2004)

D. Whitby, A. Stossel, C.D. Wang, C.Gamache, J. Papin, M. Bosch, A. Smith, D. Kedes, G. White, RC. Kennedy and D.P. Dittmer, “A novel Kaposi’s Sarcoma-associated herpesvirus (KSHV/HHV-8) homolog in Baboons”, J. Virology 77, 8159-8165 (2003)

D.P. Dittmer “ Transcription of Kaposi’s Sarcoma-associated herpesvirus in Kaposi’s Sarcoma lesions”, Cancer Research 63, 2010-2015 (2003)

J.F. Papin, W. Vahrson, and D.P. Dittmer. “SYBR-based real-time quantitative PCR for West Nile Virus circumvents potential false negative results due to strain variability”, J. Clinical Microbiology 43, 1511-1518 (2004)

B. Damania, J.H. Jeong, B. Bowser, S. DeWire M. Staudt and D. P. Dittmer “A Functional Comparison of Rta Transactivator Proteins of Gamma-2 Herpesviruses”, J. Virology 78, 5491-5499 (2004)

J. H. Jeong, J. Opela, W. Kim, C. McMurtry, R. Renne, D.P. Dittmer “Regulation of the core promoter for the latency-associated nuclear antigen (LANA) of Kaposi’s Sarcoma-associated herpesvirus”, J. Biological Chemistry 279, 16822-16831 (2004)

M.R. Staudt, Y. Kanan, J.H. Jeong, J.F. Papin, R. Hines-Boykin, D.P. Dittmer “The tumor microenvironment controls primary effusion lymphoma growth in vivo”, Cancer Research 64(14), 4790-9 (2004)

R.A. Floyd, J.E. Schneider, Jr., and D.P. Dittmer “Methylene Blue Photoinactivation of RNA Viruses”, Antiviral Research 61(3), 141-51 (2004)

D.P. Dittmer, W. Vahrson M. Staudt, J. Papin, R. Hines-Boykin and F. Fakhari “Real-time quantitative PCR arrays for virally associated cancers”, Cancer Genomics and Proteomics 1, 117-124 (2004)

T. Kalina, H. Lu, Z. Zhao, E. Blewett, D.P. Dittmer, J. Randolph-Habecker, D. G. Maloney, R. G. Andrews, H.-P. Kiem, J. Storek, “De novo generation of CD4 T cells against viruses present in the host during immune reconstitution”, Blood 105, 2410-2414 (2005)

D.P. Dittmer, W. Vahrson, M. Staudt, C. Hilscher, F.D. Fakhari, “Kaposi’s Sarcoma in the era of HAART—An update on mechanisms, diagnostics and treatment”, AIDS Rev. 7(1):56-61 (2005)

Dittmer DP, Gonzalez CM, Vahrson W, DeWire SM, Hines-Boykin R, Damania B.  Whole-genome transcription profiling of rhesus monkey rhadinovirus. J Virol. Jul;79(13):8637-50.  (2005)

Kurokawa M, Ghosh SK, Ramos JC, Mian AM, Toomey NL, Cabral L, Whitby D, Barber GN, Dittmer DP, Harrington WJ Jr.  Azidothymidine inhibits NF-kappaB and induces Epstein-Barr virus gene expression in Burkitt lymphoma.  Blood.  Jul 1;106(1):235-40.  2005

Papin JF, Floyd RA, Dittmer DP.  Methylene blue photoinactivation abolishes West Nile virus infectivity in vivo. Antiviral Res. 2005 Nov;68(2):84-7.

Chang H, Dittmer DP, Shin YC, Hong Y, Jung JU.  Role of Notch signal transduction in Kaposi's sarcoma-associated herpesvirus gene expression. J Virol. 2005 Nov;79(22):14371-82.

Hilscher C, Vahrson W, Dittmer DP.  Faster quantitative real-time PCR protocols may lose sensitivity and show increased variability. Nucleic Acids Res. 2005 Nov 27;33(21):e182.

Dittmer DP.   Profiling viral gene expression in lymphomas. Braz J Infect Dis. 2005 Oct;9(5):444.

Fakhari FD, Jeong JH, Kanan Y, Dittmer DP.  The latency-associated nuclear antigen of Kaposi sarcoma-associated herpesvirus induces B cell hyperplasia and lymphoma. J Clin Invest. 2006 Mar;116(3):735-42.

Wolf RF, Rogers KM, Blewett EL, Dittmer DP, Fakhari FD, Hill CA, Kosanke SD, White GL, Eberle R.  A naturally occurring fatal case of Herpesvirus papio 2 pneumonia in an infant baboon (Papio hamadryas anubis). J Am Assoc Lab Anim Sci. 2006 Jan;45(1):64-8.

Wang L, Dittmer DP, Tomlinson CC, Fakhari FD, Damania B.  Immortalization of primary endothelial cells by the K1 protein of Kaposi's sarcoma-associated herpesvirus. Cancer Res. 2006 Apr 1;66(7):3658-66.

Staudt MR, Dittmer DP.  Promoter switching allows simultaneous transcription of LANA and K14/vGPCR of Kaposi's sarcoma-associated herpesvirus. Virology. 2006 Jun 20;350(1):192-205.

An FQ, Folarin HM, Compitello N, Roth J, Gerson SL, McCrae KR, Fakhari FD, Dittmer DP, Renne R.  Long-term-infected telomerase-immortalized endothelial cells: a model for Kaposi's sarcoma-associated herpesvirus latency in vitro and in vivo. J Virol. 2006 May;80(10):4833-46.

Wolf RF, Papin JF, Hines-Boykin R, Chavez-Suarez M, White GL, Sakalian M, Dittmer DP.  Baboon model for West Nile virus infection and vaccine evaluation. Virology. 2006 Nov 10;355(1):44-51.

Whitby D, Marshall VA, Bagni RK, Miley WJ, McCloud TG, Hines-Boykin R, Goedert JJ, A Conde B, Nagashima K, Mikovits J, Dittmer DP, Newman DJ.  Reactivation of Kaposi's sarcoma-associated herpesvirus by natural products from Kaposi's sarcoma endemic regions. Int J Cancer. 2006.

Sin SH, Roy D, Wang L, Staudt MR, Fakhari FD, Patel DD, Henry D, Harrington WJ, Damania BA, Dittmer DP.  Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling. Blood. 2006.

Staudt MR, Dittmer DP.  The Rta/Orf50 transactivator proteins of the gamma-herpesviridae. Curr Top Microbiol Immunol. 2007;312:71-100. 2006.

Petre CE, Sin SH, Dittmer DP.  Functional p53 signaling in Kaposi's sarcoma-associated herpesvirus (KSHV) lymphomas-implications for therapy. J Virol. 2006.

Mutlu AD, Cavallin LE, Vincent L, Chiozzini C, Eroles P, Duran EM, Asgari Z, Hooper AT, La Perle KM, Hilsher C, Gao SJ, Dittmer DP, Rafii S, Mesri EA.  In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma. Cancer Cell. 2007 Mar;11(3):245-58.

Dittmer DP, Damania B. KSHV-associated disease in the aids patient..Cancer Treat Res. 2007;133:129-39.

Nun TK, Kroll DJ, Oberlies NH, Soejarto DD, Case RJ, Piskaut P, Matainaho T, Hilscher C, Wang L, Dittmer DP, Gao SJ, Damania B.  Development of a fluorescence-based assay to screen antiviral drugs against Kaposi's sarcoma associated herpesvirus. Mol Cancer Ther. 2007 Aug;6(8):2360-70.



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