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Research |
Hereditary Hemochromatosis
Hereditary Hemochromatosis Research Paper
Hereditary Hemochromatosis 10
Facts to Know |
1)Idiopathic or Hereditary hemochromatosis is a genetic disorder of metabolism in which the body absorbs iron in amounts greater than required for maintenance, generally about four times the normal amount. |
2)Hemochromatosis can develop into diseases such as diabetes, hepatic cirrhosis, heart trouble, arthritis, liver disease, neurological problems, depression, impotence, infertility, and cancer. |
3)Thirty-two million people in America (1 in 10) have the hemochromatosis gene mutation and are carriers of the disease. |
4)One and a half million people (1 in 250) have the double mutation and have hereditary hemochromatosis. |
5)Hereditary hemochromatosis is one of the most common genetic diseases affecting people of Northern European descent, butit is under-diagnosed due to clinician’s lack of sufficient awareness. |
6)If Hereditary hemochromatosis is left untreated, it progresses from iron over-absorption to iron overload to organ damage. |
7)At least 50% of men and 25% of women with the disease are likely to develop life-threatening complications. |
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8)In 1996 it was discovered that defects in the HFE gene, which help regulate the amount of iron absorbed from food, were associated with hereditary hemochromatosis. |
9)Patients can now be tested for mutations of the HFE gene with two simple and inexpensive blood tests that measure iron levels. |
10)Ask your doctor to test your iron levels because inexpensive, effective therapy is available, especially at early stages of the disease. |
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Links |
| *http:www.digestive.niddk.nih.gov/ddiseases/pubs/hemochromatosis/index.htm |
| *http://www.irondisorders.org/disorders/hem/ |
| *http://www.cdc.gov/hemochromatosis |
| *http://www.acponline.org |
Last updated: April 17, 2004