February 2014 Congratulations to Kate and Alex!
Both Kate Hacker and Alexandra Arreola have successfully defended their theses in February of 2014. We wholeheartedly congratulate them on this wonderful accomplishment.
February 2014 Brooks et. al. accepted for publication in European Urology
The ClearCode34 biomarker was used to classify tumors in to good, intermediate, and poor risk groups, outperforming conventional clinical risk algorithms. In press in European Urology
February 2014 Upcoming Thesis Defences!
Kate Hacker - February 20, 2014 at 9:00 AM, in the Bioinformatics Building, Room 1131
Alexandra Arreola - February 25, 2014 at 1:30 PM, in the Bioinformatics Room 1131
December 2013 Samira Brooks Wins a Travel Award from the Society of Toxicology
The Society of Toxicology’s (SOT) 53rd Annual Meeting and ToxExpo will be held March 23–27, 2014, at the Phoenix Convention Center in Phoenix, Arizona. The SOT Annual Meeting is the largest meeting of its kind. This annual event features a broad range of scientific sessions and a thematic program that provides participants with a unique opportunity to deepen their knowledge in topical areas and interact with leaders in their respective disciplines. The scientific program includes a plenary session, the MRC Lecture, symposia, workshops, roundtable discussions, informational sessions, historical highlights sessions, as well as platform and poster sessions. The Society anticipates that more than 6,500 toxicologists from more than 50 countries will attend. The SOT Annual Meeting also features the ToxExpo, which is the largest exhibition, dedicated to toxicology and the biomedical sciences. The exhibition features 350 exhibitors, exhibit-hosted sessions, and the opportunity to debut cutting-edge products, services, and technologies.
October 2013 Kate Hacker's Paper is Published in the Genome Research
Congratulations to Kate Hacker, whose paper has been accepted and published by Genome Research. The paper was published online on December 26, 2013. Please read below for a brief overview of the paper, and click here to access the full article online.
Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects.
September 2013 Neal Rasmussen Defends his PhD Thesis
Congratulations to Neal Rasmussen, who successfully defended his PhD Thesis on September 25, 2013. We wholeheartedly congratulate him on this wonderful accomplishment.
September 2013 Dr. Zufan Debebe Wins the AACR Travel Award
Congratulations Zufan Debebe, winner of an American Association for Cancer Research (AACR) Travel Award. Please click here for more information about AACR travel awards.
July 2013 Neal Rasmussen's Paper is Published in the Journal of Biological Chemistry
Congratulations to Neal Rasmussen, whose paper has been accepted and published by the Journal of Biological Chemistry. The paper was published online on July 26, 2013. Please read below for a brief overview of the paper, and click here to access the full article online.
Receptor Tyrosine Kinase-like Orphan Receptor 2 (Ror2) Expression Creates a Poised State of Wnt Signaling in Renal Cancer.
May 2013 Kate Hacker wins the Gertrude B. Elion Mentored Medical Student Research Award
Congratulations to Kate Hacker, winner of the Gertrude B. Elion Mentored Medical Student Research Award. The Gertrude B. Elion Mentored Medical Student Research Award will provide an annual award to one student in the amount of $10,000. These awards will support women medical students who are interested in pursuing health-related research projects. Students must have an interest in health research, and must have the support of a faculty mentor. Please click here for more information about the award.
Gertrude Belle Elion (January 23, 1918 – February 21, 1999) was an American biochemist and pharmacologist, and a 1988 recipient of the Nobel Prize in Physiology or Medicine. Working alone as well as with George H. Hitchings, Elion developed a multitude of new drugs, using innovative research methods that would later lead to the development of the AIDS drug AZT.
April 2013 Sudarshan Mohan wins a SURF Award
Congratulations to Sudarshan Mohan, winner of a Summer Undergraduate Research Fellowship Award. Please click here for more information about the award.
March 2013 Dr. Zufan Debebe wins a 2013 UNCF/Merck Science Initiative Award
Congratulations to Dr. Zufan Debebe, who has won the 2013 UNCF Merck Postdoctoral Science Fellowship, an award targeted towards providing opportunities for post-doctoral fellows to conduct original research. Please click here for more information about the award.
February 2013 Congratulations to Samira Brooks
Congratulations to Samira Brooks, who won third place for her poster entitled "Prognostic biomarker discovery for a distinct gene signature in clear cell Renal Cell Carcinoma" at the Spring 2013 North Carolina Society of Toxicology (NC SOT) meeting at the U.S. Environmental Protection Agency in Research Triangle Park, NC. A brief overview of her project is given in the January 2013 Rathmell Lab news update (below). Please click here for more information on the Spring 2013 NC SOT Meeting.
January 2013 Congratulations to Samira Brooks
Congratulations to Samira Brooks, who won first prize for her poster entitled "Prognostic biomarker discovery for a distinct gene signature in clear cell Renal Cell Carcinoma" at the 2013 UNC Toxicology program retreat. Below is a brief overview of her project:
The incidence of adult Renal Cell Carcinoma (RCC), or kidney cancer, is on a steady rise in the western world, with approximately 100,000 people affected in the United States and Europe in 2010. There are multiple subtypes of this disease, however, over 70% of patients with renal tumors have the clear cell (ccRCC) subtype, a tumor only recently found to be associated with a high degree of heterogeneity, that involves distinct genetic signatures. Genetic signatures have also been established as renal toxicant exposure biomarkers, which can serve as indicators of past renal injury and initial events of kidney cancer. Exploring the range of genome-wide expression alterations as a result of tumor heterogeneity and chronic toxicant exposure will enhance the understanding of this disease and shed light on future methods to provide a personalized care plan for patients with ccRCC.
December 2012 Kate Hacker Receives the Lineberger Cell Biology Training Grant
Congratulations to Kate Hacker (Genetics and Molecular Biology), the recipient of the Lineberger Cancer Cell Biology Training Grant. This grant supports talented students to develop a well-rounded experience integrating basic science concepts with the detection, diagnosis, and treatment of cancer. Grant support covers two years of training, and students participate in focused coursework, career development programming, and annual retreats. Click "read more" for more information on this award. Read more.
October 2012 Congratulations to Dr. Zufan Debebe
Congratulations to Zufan Debebe, PhD, the recipient of a Lineberger Postdoctoral Fellowship for 2012-2014. Click "read more" for more information on this award. Read more.
August 24, 2012 Dr. Rathmell Gives Keynote Speech
Dr. Rathmell was a featured speaker alongside UNC Head Basketball Coach Roy Williams at the American Cancer Society's Action Network breakfast held in RTP. Dr. Rathmell spoke about her American Cancer Society funded project. Read more.