Complete list of work:

Selected Publications:

Winkle, C. C., Hanlin, C. C., Gupton, S. L. 2016. Utilizing Combined Methodologies to Define the Role of Plasma Membrane Delivery During Axon Branching and Neuronal Morphogenesis. J. Vis. Exp. (109), e53743, doi:10.3791/53743.

Menon, S., and S.L. Gupton. 2016. Building Blocks of Functioning Brain: Cytoskeletal Dynamics in Neuronal Development. Int Rev Cell Mol Biol. Elsevier Vol 322: Chapter 3: 183-246.
Winkle, C.C., and S.L. Gupton. 2016. Membrane Trafficking in Neuronal Development: Ins and Outs of Neural Connectivity. In International Review of Cell and Molecular Biology. Elsevier. Vol 322: Chapter 4: 247-280.

Menon, S., N.P. Boyer, C.C. Winkle, L.M. McClain, C.C. Hanlin, D. Pandey, S. Rothenfußer, A.M. Taylor, and S.L. Gupton. 2015. The E3 Ubiquitin Ligase TRIM9 Is a Filopodia Off Switch Required for Netrin-Dependent Axon Guidance. Developmental Cell. 35:698–712. doi:10.1016/j.devcel.2015.11.022.

Taylor, A.M., S. Menon, and S.L. Gupton. 2015. Passive microfluidic chamber for long-term imaging of axon guidance in response to soluble gradients. Lab on a chip. doi:10.1039/C5LC00503E.

Barzik, M., McClain, L. M., Gupton, S. L. & Gertler, F. B. Ena/VASP regulates mDia2-initiated filopodial length, dynamics, and function. Mol Biol Cell (2014). doi:10.1091/mbc.E14-02-0712

Winkle, C. C. McClain, L.M. Valtschanoff, J.G., Park C.S., Maglione, C. and Gupton, S.L. (2014) A novel Netrin-1-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching. J Cell Biol 205, 217–232 .

S.L. Gupton, D. Riquelme, S.K. Hughes-Alford, J. Tadros, S.S. Rudina, R.O.Hynes, D. Lauffenburger, and F.B. Gertler (2012). Mena binds α5 integrin directly and modulates α5β1 function. Journal of Cell Biology. Aug 20, 2012; 198 (4)

Dent EW, Gupton SL, Gertler FB. (2011).  The growth cone cytoskeleton in axon outgrowth and guidance. Cold Spring Harb Perspect Biol. Mar 1;3(3). pii: a001800. doi: 10.1101/cshperspect.a001800.

Gupton, S.L. and Gertler, F.B. (2010). Integrin signaling switches the cytoskeletal and exocytic machinery driving neuritogenesis. Developmental Cell.  18(5)725-36.

Gupton, S.L., and Gertler, F.B. (2007). Filopodia: the fingers that do the walking. Science STKE 2007, 400.

Gupton, S.L., Eisenmann, K., Alberts, A.S., and Waterman-Storer, C.M. (2007). mDia2 regulates actin and focal adhesion dynamics and organization in the lamella for efficient epithelial cell migration. Journal of Cell Science. 120:3475-3487.

Gupton, S.L., and Waterman-Storer, C.M. (2006). Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration. Cell 125:1361-1374.

Gupton, S.L., Collings, D.A., and Allen, N.S. (2006). Endoplasmic reticulum targeted GFP reveals ER organization in tobacco NT-1 cells during cell division. Plant Physiology and Biochemistry. 44:95-105.

Gupton, S. L., Anderson, K. L., Kole, T. P., Fischer, R. S., Ponti, A., Hitchcock-DeGregori, S. E., Danuser, G., Fowler, V. M., Wirtz, D., Hanein, D., and Waterman-Storer, C. M. (2005). Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin. Journal of Cell Biology. 168:619-631.

Ponti, A., M. Machacek, S.L. Gupton, C.M. Waterman-Storer, and G. Danuser. 2004. Two distinct actin networks drive the protrusion of migrating cells. Science. 305:1782–1786. 
Gupton, S.L., Salmon, W.C., and Waterman-Storer, C.M. (2002). Converging populations of f-actin promote breakage of associated microtubules to spatially regulate microtubule turnover in migrating cells. Current Biology. 12:891-899.;2007/400/re5;2007/400/re5!divAbstractshapeimage_3_link_0shapeimage_3_link_1shapeimage_3_link_2shapeimage_3_link_3shapeimage_3_link_4shapeimage_3_link_5shapeimage_3_link_6shapeimage_3_link_7shapeimage_3_link_8shapeimage_3_link_9shapeimage_3_link_10shapeimage_3_link_11shapeimage_3_link_12shapeimage_3_link_13shapeimage_3_link_14shapeimage_3_link_15shapeimage_3_link_16shapeimage_3_link_17shapeimage_3_link_18shapeimage_3_link_19shapeimage_3_link_20shapeimage_3_link_21shapeimage_3_link_22shapeimage_3_link_23shapeimage_3_link_24shapeimage_3_link_25shapeimage_3_link_26shapeimage_3_link_27shapeimage_3_link_28shapeimage_3_link_29shapeimage_3_link_30shapeimage_3_link_31shapeimage_3_link_32shapeimage_3_link_33shapeimage_3_link_34shapeimage_3_link_35shapeimage_3_link_36shapeimage_3_link_37shapeimage_3_link_38shapeimage_3_link_39shapeimage_3_link_40shapeimage_3_link_41shapeimage_3_link_42shapeimage_3_link_43shapeimage_3_link_44shapeimage_3_link_45shapeimage_3_link_46