Mark D. Sobsey
Professor, Department of Environmental Sciences and Engineering
Director, Environmental Microbiology Laboratory

Primary Appointment: Department of Environmental Sciences and Engineering,
    School of Public Health, University of North Carolina CB# 7431
    Chapel Hill, N.C. 27599-7431
Adjunct Appointment: Curriculum in Marine Sciences

Education
Professional Positions
Professional Societies
Honors and Awards
Publications

Course Information

ENVR 421 - Environmental Health Microbiology

ENVR 890-003 - Global Water, Sanitation and Hygiene


Education
 8/71-4/72: Department of Virology and Epidemiology, Baylor College of Medicine, Texas Medical Center, Houston, Texas.  Postdoctoral Fellow in Virology

 6/67-8/71: School of Public Health, University of California at Berkeley, Berkeley, California.  Ph.D., Environmental Health Sciences

 1/66-5/67: Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.  M.S., Hygiene

 9/61-12/6: Univ. of Pittsburgh, Pittsburgh, Pennsylvania.  B.S., Biology

Professional Positions
 7/84-Present: Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, N.C. Professor of Environmental Microbiology

 2/96-2/97: Visiting Scientist, Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA.

 7/89-8/93: Department of Environmental Sciences and Engineering University of North Carolina, Chapel Hill, N.C. Director, Environmental Chemistry and Biology Program (7/89-7/90); Director, Program in Environmental Health Sciences (7/90-8/93)

 7/79-6/84: Department of Environmental Sciences and Engineering and Department of Bacteriology and Immunology, Univ.of North Carolina, Chapel Hill, N.C. Associate Professor of Environmental Microbiology

 1/81-1/82: Visiting Scientist, Laboratory of Infectious Diseases (Hepatitis and Epidemiology Sections), National Institute of Allergy and Infectious Diseases, National
Institutes of Health, Bethesda, MD

 9/74-7/79: Department of Environmental Sciences and Engineering and Department of Bacteriology and Immunology, Univ. of North Carolina, Chapel Hill, N.C. Assistant Professor of Environmental Microbiology

 11/73-9/74: Department of Virology and Epidemiology, Baylor College of Medicine, Texas Medical Center, Houston, TX. Assistant Professor of Virology.

 4/72-11/73: Department of Virology and Epidemiology, Baylor College of Medicine, Texas Medical Center, Houston, TX., Instructor.

Professional Societies
American Society for Microbiology; American Water Works Association; International Association on Water Quality; Delta Omega.

Honors and Awards
 University of North Carolina at Chapel Hill, Kenan Study Leave, 1994

 National Institutes of Health, National Institute of Environmental Health Sciences Research Career Development Award (1 KO4 ES 00026), 1977-82.

 National Institutes of Health Post-Doctoral Fellowship, Baylor College of Medicine, 1971-72

 U.S. Public Health Service and Atomic Energy Commission Graduate Traineeships and Fellowships, University of California at Berkeley, 1967-71

 U.S. Public Health Service Graduate Traineeship, Univ. of Pittsburgh, 1966-67

 Various undergraduate scholarships, University of Pittsburgh, 1961-65

Publications (most recent 5 years because if we tried to add them all the Internet would explode)

Casteel, M.J., A. Gold. M.D. Sobsey, and M.D. Brecher. 2002. Photosensitization of hepatitis A virus and other non-enveloped RNA viruses by meso-substituted porphryins in water and human plasma. Pp. 397-402 In: Biologic Effects of Light, 2001. Holick, M.F. (ed.). Kluwer Academic Publishers, Boston.

Hill, V.R. and M.D. Sobsey (2002) Removal of Salmonella and microbial indicators in constructed wetlands treating swine wastewater. Wat. Sci. Technol., 44(11–12): 215–222.

Barrett, E.C. , M.. Sobsey, C.H.. House and K.D. White (2002) Microbial indicator removal in onsite constructed wetlands for wastewater treatment in the southeastern U.S. Wat. Sci. Technol., 44(11–12): 177–182.

Hill, V.R., A. Kantardjieff, M.D. Sobsey and P.W. Westerman (2002) Reduction of enteric microbes and nutrients in flushed swine wastewater treated by a biological aerated filter and UV irradiation. Water Environment Research, 74(1): 91-99.

Hsu, F.-C., Y.-S.C. Shieh and M.D. Sobsey (2002) Enteric bacteriophages as potential fecal indicators in ground beef and poultry meat. J. Food Prot., 65(1): 93-99.

Brion, G, J.S. Meschke and M.D. Sobsey (2002) F-specific RNA Coliphage: Occurrence, Types and Survival in Natural Waters. Wat. Res., 36(9): 2419-2425.

Meschke, J.S., and M.D. Sobsey. (2002) Human Caliciviruses: Basic Virology and Epidemiology. In: The Encyclopedia of Environmental Microbiology, G. Bitton, Ed. John Wiley and Sons, Inc. New York.

Meschke, J.S., and M.D. Sobsey (2002) Norwalk-Like Viruses: Detection Methodologies and Environmental Fate, G. Bitton, Ed. In: The Encyclopedia of Environmental Microbiology. John Wiley and Sons, Inc. New York.

Linden, K.G., G.A. Shin, G. Faubert and M.D. Sobsey (2002) UV disinfection of Giardia lamblia cysts in water. Environ. Sci. Technol., 36(11): 2519-22.

Wilson, S.M., F. Howell, S. Wing, and M. Sobsey (2002) Environmental Injustice and the Mississippi Hog Industry, Environmental Health Perspectives, 110, Supplement 2: Number 2: 195-201.

Sobsey, M.D. and L.W. Alexander (2002) Effects of Water Quality on the Inactivation of Hepatitis A Virus and Enteroviruses by Free Chlorine. In: Proc. Disinfection 2002, Water Environment Federation, Alexandria, VA.

Sobsey, M.D. (2002) Viruses in Animal Manures. In: Proceedings of the US EPA Workshop on Emerging Infectious Disease Agents and Issues Associated with Animal Manures, Biosolids and Similar By-products, June, 2001. U.S. Environmental Protection Agency, Cincinnati, Ohio.

Sobsey, M.D. (2002) Managing Water in the Home: Accelerated Health Gains from Improved Water Supply. WHO/SDE/WSH/02.02, World Health Organization, Geneva.

Noble, R.T. S.M. Allen, A.D. Blackwood, W. Chu, S.C. Jiang, G.L. Lovelace, M.D. Sobsey, J.R. Stewart and D.A. Wait (2003) Use of viral pathogens and indicators to differentiate between human and non-human fecal contamination in a microbial source tracking comparison study. J. Water and Health, 1(4): 195-208.

Cole, D.; Long, S. C., and Sobsey, M. D. Evaluation of F+ RNA and DNA Coliphages as Source-Specific Indicators of Fecal Contamination in Surface Waters. Applied and Environmental Microbiology. 2003 Nov; 69(11):6507-6514.

Hill, V. R. and Sobsey, M. D. Performance of Swine Waste Lagoons for Removing Salmonella and Enteric Microbial Indicators. Transactions of the Amer. Soc. Ag. Eng. 2003 May-2003 Jun 30; 46(3):781-788.

Ko, G., T.L. Cromeans and M.D. Sobsey (2003) Detection of Infectious Adenovirus in Cell Culture by mRNA Reverse Transcription-PCR. Appl. Environ. Microbiol., 69(12): 7377-7384.

Shin, G. A. and Sobsey, M. D. (2003) Reduction of Norwalk Virus, Poliovirus 1, and Bacteriophage MS2 by Ozone Disinfection of Water. Applied and Environmental Microbiology, 69(7):3975-3978

Sobsey MD, Handzel, T., and L. Venczel (2003) Chlorination and safe storage of household drinking water in developing countries to reduce waterborne disease. Water Sci. Technol., 47(3):221-8

Sobsey MD, Perdue R, Overton M, and J. Fisher (2003) Factors influencing faecal contamination in coastal marinas. Water Sci. Technol., 47(3):199-204.

Simmons OD 3rd, Sobsey MD. (2003) A chemiluminescent immunofocus assay (CIFA) for non-microscopic enumeration of Cryptosporidium parvum infectivity in cell culture. Water Sci. Technol., 47(3):137-42.

Meschke JS, Sobsey MD. (2003) Comparative reduction of Norwalk virus, poliovirus type 1, F+ RNA coliphage MS2 and Escherichia coli in miniature soil columns. Water Sci. Technol., 47(3):85-90.

Thompson, T, Sobsey. M., and J. Bartram (2003) Providing clean water, keeping water clean: an integrated approach. Int J Environ Health Res., 13 Suppl. 1:S89-94.

Cole, D.J., V.R. Hill, D.A. Wait and M.D. Sobsey (2003) Microbial Impacts of Animal Wastes and other Fecal Wastes on Water Resources . University of North Carolina Water Resources Research Institute, Raleigh, NC. In Press.

Sobsey, M.D. and J. Bartram (2002) Water Quality and Health in the New Millennium: The Role of the World Health Organization Guidelines for Drinking-water Quality. In: Proceedings 17 th International Congress for Nutrition. S. Karger Medical and Scientific Publishers, New York.

Sobsey, M.D. and F. Pfaender (2003) Critical Review and Evaluation of the H 2S Method for Detection of Fecal Contamination of Drinking Water, Report to the World Health Organization, Geneva.

Craun, G.F., F. Frost, M.D. Sobsey and T. Whittam (2003) The Potential Use of Virulence Factor Activity Relationships to Help Classify Microbial Drinking Water Contaminants for the Environmental Protection Agency’s Contaminant Candidate List, 79 pages. Report to the US Environmental Protections Agency, Washington, DC.

Linden, K.G., J. Oliver and M.D. Sobsey (2003) Fate and Persistence of Pathogens Subjected to Disinfection. 98-HHE-2, 86 pages. Water Environment Research Foundation, Alexandria, VA.

Sobsey, M.D. and V.R. Hill (2003) Reductions of Enteric Microbes in Swine Lagoons and Alternative Biological Treatment Systems. University of North Carolina Water Resources Research Institute, Raleigh, NC.

Casteel, M.J., A. Gold, L.M. Ball, and M.D. Sobsey (2003) Photosensitization of Hepatitis A Virus (HAV) and Other Microbes by Meso-substituted Porphyrins in Water. In: Proceedings AWWA Water Quality Technology Conference. American Water Works Association, Denver.

Aitken, M.., MD. Sobsey, G.W. Walters, V.Hill, M. Shehee, K.Blauth, P.E. Crunk, J. Willis, P. Schafer, J. Farrell, C. Arnett and B. Turner “Evaluation of Thermophilic Anaerobic Digestion to Meet Class A Biosolids Criteria” In: Proceedings of the Water Environment Federation Technical Conference and Exposition, Water Environment Federation, Alexandria.

Willis, J., M. Aitken, C. Arnett, T. Hull, P. Schafer, M. Sobsey, B. Turner “CBFT3: PEC Negotiation and Cost Analysis” In: Proceedings of the Water Environment Federation Technical Conference and Exposition, Water Environment Federation, Alexandria.

Ko, G.P., T. Cromeans and M.D. Sobsey (2003) UV Inactivation of Adenovirus Type 41 measured by Cell Culture mRNA RT-PCR. In: Proceedings of the International Conference of UV Disinfection, 10 pages. University of Vienna School of Veterinary Medicine, Vienna.

Newland, S., G.-A. Shin, and M.D. Sobsey (2003) Comparative Inactivation of Norwalk Virus, Poliovirus 1, and Coliphage MS2 in Water by Low Pressure UV radiation. In: Proceedings of the International Conference of UV Disinfection, 14 pages. July 2003, University of Vienna School of Veterinary Medicine, Vienna.

Shin, G.-A, K.G. Linden, J.P. Dubey, and M.D. Sobsey (2003) Disinfection of Toxoplasma gondii in water by UV Radiation. In: Proceedings of the International Conference of UV Disinfection, 10 pages. University of Vienna School of Veterinary Medicine, Vienna.

Simmons, O.D., III and M.D. Sobsey (2003) Evaluation of Alternative Swine Waste Treatment and Management Technologies for Control of Pathogens. In: Proceedings of the 2003 North Carolina Animal Waste Management Workshop: Progress on the Development of Alternative Technologies for the Processing and the Use of Animal Waste, North Carolina State University, Raleigh, NC.

Aitken, M., M.D. Sobsey, G.W. Walters, M. Shehee, P.L. Crunk, K.E. Blauth, V.R. Hill,[1] and S.P. Nappier (2003) Evaluation of Pathogen and Indicator Organism Removal During Continuous and Batch Thermophilic Anaerobic Digestion of Wastewater Sludge. 80 pages. Final Report. Submitted to Brown and Caldwell, Inc., Atlanta, GA.

Willits, D.H., M. M. Peet, J. Cheng, M. Sobsey, K. Keener, E. Estes and K. D. Zering (2003) Using a Greenhouse Tomato Crop to Recover Bio-Resources From Swine Waste, 42 pages. Final Report. NCARS Project No. NC05885. North Carolina State University. Raleigh, NC.

Sobsey, M.D. (2003) Hepatitis A Virus and Other Enteropathogens in Foods. ASPH/CDC Cooperative Agreement. Project Number: S1103-19/20. Final Report. Association of Schools of Public Health, Washington, DC.

Sobsey, M.D. and G. Lovelace (2003) Mission Bay Epidemiological Study - Coliphage Analysis of Recreational Water, 18 pages. Final Report. Southern California Coastal Water Research Project. Irvine, Ca.

Sobsey, M.D. and M.E. Anderson (2003) Detection and Occurrence of Antimicrobially Resistant Enteric Bacteria on or Near Swine Farms in Eastern North Carolina, 217 pages. Final Report. Robert Wood Johnson Foundation.

Sobsey, M.D. and Meschke (2003) Virus Survival in the Environment with Special Attention to Survival in Sewage Droplets and Other Environmental Media of Fecal or Respiratory Origin. Report for the World Health Organization, 70 pages, Geneva, Switzerland.

Sobsey, M.D. and S. Gundry (2003) Research Agenda for WHO International Network to Promote Household Treatment and Safe Storage, 18 pages. International Network to Promote Household Treatment and Safe Storage of Drinking Water. World Health Organization, Geneva.

Sobsey, M.D., G. Ko, O.D. Simmons, III , C. Likirdopulos, L. Worley-Davis (2003) Evaluation of Alternative Technologies for Pathogens, 58 pages. Annual Report. Project OPEN Science Team for Pathogens. Animal and Poultry Waste Management Center. North Carolina State University. Raleigh, NC.

Casteel, M.J., Jayaraj, K., Gold, A., Ball, L.M., and Sobsey, M.D. (2004) Photoinactivation of Hepatitis A Virus by Synthetic Porphyrins. Photochem. Photobiol. 80: 294-300.

Dayan, G. H.; Rodriguez, R.; Vinje, J.; Vasconez, N.; Caceres, V.; Gregoricus, N.; Sobsey, M., and M. Landaverde (2004) Assessment of Areas at Increased Risk for Poliovirus Circulation in Ecuador. Epidemiology and Infection, 132(5):787-795.

Francy, D. S.; Simmons, O. D.; Ware, M. W.; Granger, E. J.; Sobsey, M. D., and F.W. Schaefer, (2004) Effects of Seeding Procedures and Water Quality on Recovery of Cryptosporidium Oocysts From Stream Water by Using Us Environmental Protection Agency Method 1623. Applied and Environmental Microbiology, 70(7):4118-4128.

Kashinkunti, R.D., K.G. Linden, G.-A. Shin, D.H. Metz, M.D. Sobsey, M.C. Moran, and A.M. Samuelson (2004) Investigating multibarrier inactivation for Cincinnati—UV, by-products, and biostability. J. Amer. Water Works Assoc., 95(6): 114-127. (available on-line)

Long, S.C,, and M.D. and M. Sobsey (2004) A comparison of the survival of F+RNA and F+DNA coliphages in lake water microcosms. J Water Health, 2(1):15-22.

Shehee, M.W. and M.D. Sobsey (2004) Development of a L-Rhamnose and D-Arabitol Supplemented Macconkey Agar to Identify Pathogenic Yersinia enterocolitica among Environmental Yersinias in Swine Production Wastes. Journal of Microbiological Methods, 57(2):289-292.

Sobsey M.D. and J. Bartram (2003) Water quality and health in the new millennium: the role of the World Health Organization Guidelines for Drinking-Water Quality. Forum Nutr., 56:396-405.

Sobsey, M.D.; Yates, M. V.; Hsu, F. C.; Lovelace, G.; Battigelli, D.; Margolin, A.; Pillai, S. D., and N. Nwachuku (2004) Development and Evaluation of Methods to Detect Coliphages in Large Volumes of Water. Water Science and Technology, 50(1):211-217.

Venczel, L. V.; Likirdopulos, C. A.; Robinson, C. E., and M.D. Sobsey (2004) Inactivation of Enteric Microbes in Water by Electro-Chemical Oxidant From Brine (NaCl) and Free Chlorine. Water Science and Technology, 50(1):141-146.

Vinje, J., Oudejans, S.J., Stewart, J.R., Sobsey, M.D., and S.C. Long (2004) Molecular detection and genotyping of male-specific coliphages by reverse transcription-PCR and reverse line blot hybridization. Appl Environ Microbiol., 70(10):5996-6004.

Vinje, J.; Hamidjaja, R. A., and M.D. Sobsey (2004) Development and Application of a Capsid Vp1 (Region D) Based Reverse Transcription PCR Assay for Genotyping of Genogroup I and II Noroviruses. Journal of Virological Methods., 116(2):109-117.

Wetz, J. J.; Lipp, E. K.; Griffin, D. W.; Lukasik, J.; Wait, D.; Sobsey, M. D.; Scott, T. M., and J.B. Rose (2004) Presence, Infectivity, and Stability of Enteric Viruses in Seawater: Relationship to Marine Water Quality in the Florida Keys. Marine Pollution Bulletin., 48(7-8):698-704.

Guidelines for Drinking-water Quality, 3rd edition. Volume 1. Recommendations (2004) World Health Organization, Geneva. (One of 22 named contributors to these Guidelines and a member of the Microbial Aspects Working Group).

Linden, K.G., J. Oliver, M.D. Sobsey and G-A. Shin (2004) Fate and Persistence of Pathogens Subjected to Disinfection. WERF Report (Project 98-HHE-2). Pages: 200 · ISBN: 1843396998. Water Environment Research Foundation, Alexandria, VA.

Sobsey, M.D., J.A. Kase , O.D. Simmons, III, and K. Swanson (2004) Evaluation of the Proposed OWASA Water Reclamation System for Production of Non-Potable Reuse Water for UNC Chapel Hill. Final Report. UNC Energy Services and OWASA, 90 pages. Chapel Hill.

Aitken, M.D. , M.D. Sobsey, N.A. Van Abel, K.E. Blauth, P.L. Crunk, M.E. Meisch and C.C. Nichols (2004) Inactivation of Escherichia coli O157:H7 During Thermophilic Anaerobic Digestion of Manure from Dairy Cattle, Proceedings of 10th World Congress on Anaerobic Digestion, International Water Association, Montreal, Canada.

Bos, R. and M.D. Sobsey (2004) Final Report. WHO/IWA Seminar on Water and Health. Post-conference Event of the 4th IWA Water Congress, Sept. 13-19, 2004, 25 pages, WHO, Geneva.

Kase, J.A. and M.D. Sobsey (2004) Progress Report Number 1. Stability and Recovery of Norovirus from Porous and Non-porous Surfaces as Measured by Quantitative RT-PCR., 8 pages. Sterilox Technologies, Philadelphia, PA, UNC-Chapel Hill.

Sobsey, M.D. (2004) Drinking Water and Health Research: A Look to the Future. In: Proceedings of the National Symposium on Current Critical Questions in Research on Drinking Water and Health, Brita Water Institute, San Francisco, CA

Sobsey, M.D., B.H. Olson and S. Pillai (2004) Where will future emerging pathogens come from? What approaches can we use to find them, in addition to VFARs? In: Proceedings of the National Workshop on Virulence Factor Activity Relationships., 17 pages. US EPA, Washington, DC.

Sanders, B., A. Horne, R. Keller and M.D. Sobsey (2004) Identification and Control of Non-Point Sources of Microbial Pollution in a Coastal Watershed. Final Report, 25 pages. US EPA STAR Project. US EPA, Washington, D.C.

Sobsey, M.D., M. Casteel., T. Cromeans, J. Vinje, J. Narayanan, and D. Love (2004) Development of Viral Extraction, Processing and Detection Methods for Food Commodities, 175 pages. Final Report U.S. Food and Drug Administration, Project No. FD-U-001957-01. Washington, D.C.

Sobsey, M.D. (2004) Hepatitis A Virus and Other Viruses in Foods, Water and Wastes. Project Number: S1727-21/21, Final Report, 100 pages, ASPH/CDC Cooperative Agreement, Washington, DC and Atlanta, GA. UNC-Chapel Hill.

Sobsey, M.D., J. Vinje and J.S. Meschke. Methods for the Detection of Viruses in Water: Principles and Procedures. Final Report, 175 pages. Environmental Protection Agency of Denmark, Copenhagen, DE.

Sobsey, M.D., L. Casanova and O.D. Simmons, III (2004) Reduction of Pathogens in Water by Procter & Gamble PUR. Annual Report, 21 Pages. Submitted to Procter & Gamble, Cincinnati, Ohio, UNC-Chapel Hill, NC.

Sobsey, M.D., O.D. Simmons, , III, C. Likirdopulos and L. Worley-Davis (2004) Evaluation of Alternative Swine Waste Treatment Technologies for Pathogens. Annual Report, 160 pages. Smithfield Foods, Premium Standard Foods and NC Attorney General’s Office. North Carolina State University, Raleigh, NC.

Sobsey, M.D., S. Goyal, A. Margolin, and Suresh Pillai (2004) Validation of Methods to Detect Coliphages in Groundwater. Final Report, 90 pages. Health and Ecological Criteria Division, Office of Science & Technology, US EPA, Washington, D.C.

Gundry, S.W., Sobsey, M. and J. Wright (2005) Household Water Treatment and Storage. Waterlines, 23: (3), p.14.

Cromeans, T., .J Narayanan, K. Jung, G. Ko, D. Wait and M. Sobsey (2005) Development of Molecular Methods to Detect Infectious Viruses in Water, Pages: 128 · ISBN: 1843398915, American Water Works Association Research Foundation, Denver.

Sickbert-Bennett. E.E., Weber, D.J., Gergen-Teague M.F., Sobsey, M.D., Samsa, G.P., and W.A. Rutala (2005) Comparative efficacy of hand hygiene agents in the reduction of bacteria and viruses. Am J Infect Control., 33(2):67-77.

Shin, G.A., K.G. Linden, and M.D. Sobsey (2005) Low pressure ultraviolet inactivation of pathogenic enteric viruses and bacteriophages. J. Environ. Eng. Sci./Rev. gen. sci. env. 4(S1): S7-S11 (2005)

Cromeans, T. and M.D. Sobsey (2005) Development of Molecular Methods for Detection of Infectious Viruses in Treated Wastewater, WERF Report (Project 99-HHE-5UR), Water Environment Research Foundation, Alexandria, VA.

Sobsey, M.D. (2005) Viruses in Animal Manures, pp. 107-118, In: Contemporary Perspectives on Infectious Disease Agents in Sewage Sludge and Manure. J.E. Smith, Jr., P.D. Milner, W. Jakubowski, N. Goldstein and R. Rynk (eds.), Compost Science and Utilization, The JG Press, Emmaus, PA.

Characklis, G.W., M.J. Dilts, O.D. Simmons III, C.A. Likirdopulos, L-A. H. Krometis, and M.D. Sobsey (2005) Microbial Partitioning to Settleable Particles in Stormwater. Water Research, 39(9):1773-82.

Jothikumar N, Cromeans TL, Sobsey MD, Robertson BH. 2005b Development and evaluation of a broadly reactive TaqMan assay for rapid detection of hepatitis A virus. Appl. Environ. Microbiol., 71(6): 3359-63

Jothikumar N, Cromeans TL, Hill VR, Xiaoyan L, Sobsey MD, Erdman DD. 2005c Quantitative Real-time PCR Assays for Detection of Human Adenoviruses and Differentiation of Serotypes 40 and 41. Appl. Environ. Microbiol. , 71(6): 3131-6.

Long, S.C., S.S. El-Khoury, S. Oudejans, M.D. Sobsey and J. Vinje (2005) Assessment of Sources and Diversity of Male-Specific Coliphages for Source Tracking. J. Env. Eng. Sci., 22(3): 366-377.

Ko G, Narayanan, J, V.R. Hill and M.D. Sobsey (2005) Rapid Detection of Infectious Adenoviruses by mRNA Real-Time RT-PCR. J. Virological Methods, 127(2): 148-53.

Cole. D., Drum, D.J., Stalknecht, D.E., White, D.G., Lee, M.D., Ayers, S., Sobsey, M., and J.J. Maurer (2005) Free-living Canada geese and antimicrobial resistance. Emerg. Infect. Dis., 11(6):935-8.

Ko, G., T.L. Cromeans and M.D. Sobsey (2005) UV inactivation of adenovirus type 41 measured by cell culture mRNA RT-PCR. Water Res., 39(15):3643-9.

Aitken M.D., Sobsey, M.D., Blauth, K.E., Shehee, M., Crunk, P.L., and G.W. Walters (2005) Inactivation of Ascaris suum and poliovirus in biosolids under thermophilic anaerobic digestion conditions. Environ. Sci. Technol., 39(15):5804-9.

Aitken, M.D., M.D. Sobsey, M. Shehee, K.E. Blauth, V.R. Hill, J.B. Farrell, S.P. Nappier, G.W. Walters, P.L. Crunk, and N. Van Abel (2005) Laboratory Evaluation of Thermophilic Anaerobic Digestion to Produce Class A Biosolids. 2. Inactivation of Pathogens and Indicator Organisms in a Continuous-flow Reactor Followed by Batch Treatment, Water Environment Research, 77: 3028-3036.

Hendricks, D.W., W.F. Clunie, G.D. Sturbaum, D.A. Klein, T.L. Champlin, P. Kugrens, J. Hirsch, B. McCourt, G.R. Nordby, M.D. Sobsey, D. J. Hunt, and M.J. Allen (2005) Filtration Removals of Microorganisms and Particles. J. Environ. Eng., Amer. Soc. Civil Engineers, 131(12): 1621-1632.

Likirdopulos, C. A., O. D. Simmons, III, G.P. Ko, and M. D. Sobsey. 2005.  Evaluation of an Alternative Swine Waste Treatment Technology in North Carolina for the Reduction of Microbial Indicators and Salmonella Pathogens.  In: Proceedings of the 2005 Animal Waste Management Symposium, Research Triangle Park, NC.

Likirdopulos, C. A., O. D. Simmons, III, D. W. Watson, and M. D. Sobsey.  2005.  Collection Methods for Evaluating Microbial Indicator Concentrations of House Flies (Musca Domestica) on Swine Farms in Eastern North Carolina.  In: Proceedings of the 2005 Animal Waste Management Symposium, Research Triangle Park, NC.

Sullivan, M.A., R.J. Chihara, C.A. Likirdopulos, O.D. Simmons, III, and M.D. Sobsey.  2005.  Antimicrobial Resistance of E. coli and Salmonella on Swine Farms in Eastern North Carolina.  In: Proceedings of the 2005 Animal Waste Management Symposium, Research Triangle Park, NC.

Ko, G.P., O.D. Simmons, III, C.A. Likirdopulos, and M.D. Sobsey.  2005.  Investigation of Airborne Releases of Microbial Contaminants from Swine Farms in North Carolina.  In: Proceedings of the 2005 Animal Waste Management Symposium, Research Triangle Park, NC.

Chihara, R.J., M.A. Sullivan, C.A. Likirdopulos, O.D. Simmons, III, C.L. Burch and M.D. Sobsey.  2005.  Comparison of Methods for Detection of Fecal Coliforms and E. coli in Agricultural and Municipal Wastewater Systems.  In: Proceedings of the 2005 Animal Waste Management Symposium, Research Triangle Park, NC.

Simmons, III, O.D., C.A. Likirdopulos, L. Worley-Davis, C.M. Williams and M.D. Sobsey.  2005.  Anaerobic Digestion as an Alternative Treatment for Microbial Pathogens in North Carolina Swine Wastes from Confined Animal Feeding Operations (CAFOs).  In: Proceedings of the 2005 Animal Waste Management Symposium, Research Triangle Park, NC.

Park, G.W. and M.D. Sobsey (2005) Evaluation of efficacy test of Sterilox Technologies products on norovirus and bacteriophage MS2, Report #3, 23 pages, Report to Sterilox Technologies, UNC, Chapel Hill

Sobsey, M.D., C.M. Williams, C. Ohl, K. Blauth and O.D. Simmons, III (2005) Impact of Pathogenic and Antibiotic Resistant Bacteria on Water Quality On or Near Swine Farms. Annual Progress Report, NCDHHS Contract, UNC, Chapel Hill.

Sobsey, M.D., G. Lovelace D. Love and J. Murphy (2005) F+ Coliphages as Source Tracking Viral Indicators of Fecal Contamination in Coastal Waters and Shellfish, Annual Progress Report, University of North Carolina Sea Grant College Program, Raleigh

Stauber, C.E., G.M. Ortiz, M.A. Elliott, and M.D. Sobsey (2005) Field characterization of the biosand filter for household drinking water in the Dominican Republic, 8 pages. In Proc. AGUA 2005, International Seminar: “Integral Vision for the Water Quality Improvement". Cali, Colombia

Sobsey, M.D. (2006) Drinking water and health research: a look to the future in the United States and globally. J. Water Health, 4 (Supplement 1): 17-21.

Sobsey, M.D. (2006) Hepatitis A. In: Pathogens in Water, Manual #48. Amer. Water Works Assoc., 310 pages, Denver, CO.

Casteel, M.J., M.D. Sobsey and JP. Muller (2006) Fecal contamination of agricultural soils before and after hurricane-associated flooding in North Carolina, J. Environmental Science and Health (Part A - Toxic / Hazardous Substances & Environmental Engineering. 42(2): 173-174

Stewart, J.R., J. Vinje, S. Oudejans, G. Scott and M.D. Sobsey (2006) Sequence Variation among Group III F+RNA Coliphages from Waters and Swine Lagoons, Appl. Environ. Microbiol, 72(2): 1226–1230 .

Nappier, S.P., M.D.Aitken and M.D. Sobsey (2006) Male-Specific Coliphages as Indicators of Thermal Inactivation of Pathogens in Biosolids, Appl Environ Microbiol. 72(4): 2471-5.

Rutala, W.A., J.E. Peacock, M.F. Gergen, M.D. Sobsey, and D.J. Weber (2006) Efficacy of hospital germicides against Adenovirus 8, a common cause of epidemic keratoconjunctivitis in health care facilities. Antimicrobial Agents & Chemotherapy, 50(4): 1419-24.

Anderson, M.E and M. D. Sobsey (2006) Detection and occurrence of antimicrobially resistant E. coli in groundwater on or near swine farms in Eastern North Carolina. Wat. Sci. Tech., 54(3): 211–218

Stauber, C.E., M.A. Elliott, F. Koksal, G.M. Ortiz, F.A. DiGiano and M.D. Sobsey (2006) Characterization of the biosand filter for E. coli reductions from household drinking water under controlled laboratory and field use conditions, Wat. Sci. Tech., 54(3): 1–7.

Elliot, M.A., C.E. Stauber, G.M. Ortiz, F.A. DiGiano,M.D. Sobsey, F. Koksal and K. Liang (2006) Characterization of the Microbial Reductions and Flow Conditions of the Biosand Filter, a Household-Scale, Intermittently Operated Slow Sand Filter. In: Recent Progress in Slow Sand and Alternative Biofiltration Processes, R. Gimbel, N. Graham, and MR. Collins (eds.), 512 pp., IWA, London, UK

Sloane, P.D., L. Cohen, C. Williams, J. Munn, J. Preisser, M. Sobsey, D. Wait, and S. Zimmerman (2006) Effect of Specialized Bathing Systems on Resident Cleanliness and Water Quality in Nursing Homes:  A Randomized Controlled Trial. J. Water Health. In Press.

Sobsey, M.D. and F.K. Pfaender. Critical Review and Analysis of the H 2S Method for Detection of Fecal Contamination of Drinking Water. Pages: 50. Water, Sanitation and Health Programme. World Health Organization, Geneva. In Press.

Stewart-Pullaro, J., J.W. Daugomah, D.E. Chestnut, D.A. Graves, M.D. Sobsey, G.I. Scott (2006) F +RNA coliphage typing for microbial source tracking in surface waters  J. Appl. Microbiol., Published article online: 7-Jul-2006. In Press.

Colford, J.M. Jr., T.J. Wade, K.C.Schiff , C.C. Wright, John G. Griffith , S.K. Sandhu , S. Burns, J. Hayes, M. Sobsey, G. Lovelace and S.B. Weisberg (2006) Water quality indicators and the risk of illness in non-point source impacted recreational waters. Epidemiology, In Press.

Krometis. L.-A.H., G.W. Characklis; O.D. Simmons, III, M.J. Dilts, C.A. Likirdopulos, and Mark D. Sobsey (2006) Intra-Storm Variability in Microbial Partitioning and Microbial Loading Rates. Wat. Res., In Press.


 


Department of Environmental Sciences and Engineering
UNC-Chapel Hill
last updated 09/26/07