Postdoctoral Postions available September, 2007 to study the function of neural cell adhesion molecules of the L1 family (L1, CHL1, NrCAM) in axon guidance using mouse genetic models of mental retardation and autism spectrum disorder.
Specific topographic systems to be studied are the retino-collicular and thalamocortical projections. Studies and training will be conducted in axon tracing using lipophilic dyes (DiI, DiA) in mice, immunohistochemistry of mouse brain, confocal microscopy, molecular cloning, Amaxa electroporation of cortical neurons, transfection and analysis of cell and explant cultures from retina and thalamus, immunoprecipitation, immunoblotting, and kinase assays. Novel mouse genetic models will be intercrossed and genotyped for the proposed studies.
Interested post-docs are welcome to apply by sending their CV along with a brief list of references (just names and contact information; no actual references at this time, please).