Selected Publications

• Brennaman LH and Maness PF. (2010) NCAM in Neuropsychiatric and Neurodegenerative Disorders. (2010) Advances in Experimental Medicine and Biology 663:299-317.
• Buhusi M, Demyanenko GP, Jannie KM, Dalal J, Darnell EPB, Weiner JA, and Maness PF. (2009) ALCAM regulates mediolateral retinotopic mapping in the superior colliculus. Journal of Neuroscience 29:15630-15641.
• Demyanenko GP, Halberstadt AI, Rao RS, and Maness PF. (2009) CHL1 cooperates with PAK1-3 to regulate morphological differentiation of embryonic cortical neurons. Neuroscience 165:107-115.
• Moy SS, Nonneman R, Young N, Demyanenko G, and Maness PF. (2009) Impaired sociability and cognitive function in NrCAM-null mice. Behavioural Brain Research 205:123-131.
• Siesser PF and Maness PF. (2009) L1 cell adhesion molecules as regulators of tumor cell invasiveness. Cell Adhesion and Migration 3:275-277.
• Cox ET, Brennaman LH, Gable KL, LaMantia AS, Lieberman JA, Gilmore J H, Maness PF, and Jarskog LF. (2009) Developmental regulation of neural cell adhesion molecule in human prefrontal cortex. Neuroscience 162:96-105.
• Schmid RS and Maness PF. (2008) L1 and NCAM adhesion molecules as signaling coreceptors in neuronal migration and process outgrowth. Current Opinion in Neurobiology 18:1-6.
• Brennaman LH and Maness PF. (2008) Developmental regulation of GABAergic interneuron branching and synaptic development in the prefrontal cortex by soluble neural cell adhesion molecule. Molecular and Cellular Neuroscience 37:781-93.
• Buhusi M, Schlatter M, Demyanenko G, Thresher R, and Maness PF. (2008) L1 interaction with ankyrin regulates mediolateral topography in the retinocollicular projection. Journal of Neuroscience 28:177-188.
• Wright AG, Demyanenko GP, Powell A, Schachner M, Enriquez-Barreto L, Tran T, Polleux F, and Maness PF. (2008) Close Homolog of L1 (CHL1) and neuropilin1 mediate guidance of thalamocortical axons at the ventral telencephalon. Journal of Neuroscience 27.13:667-13,679.
• Schlatter MC, Buhusi M, Wright AG, and Maness PM. (2008) Close homolog of L1 (CHL1) promotes Sema3A-induced growth cone collapse and neurite elaboration through a motif required for recruitment of ERM proteins to the plasma membrane. Journal of Neurochemistry 104:731-744.
• Maness PF and Schachner M. (2007) Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migration. Nature Neuroscience 10:19-26.
• Sullivan PF, Keefe RSE, Lange LA, Lange EM, Stroup TS, Lieberman J, and Maness PF. (2007) NCAM1 and Neurocognition in Schizophrenia. Biological Psychiatry 61:902-910.
• Hinkle CL and Maness PF. (2006) Regulation of neural cell adhesion molecule function by ectodomain shedding. Recent Research Developments in Molecular and Cellular Biology 6:121-136.
• Hinkle CL, Diestel S, Lieberman J, and Maness PF. (2006) Metalloprotease-induced ectodomain shedding of neural cell adhesion molecule (NCAM). Journal of Neurobiology 66:1378-1395.
• Panicker AK, Buhusi M, Erickson A, and Maness PF. (2006) Endocytosis of ß1 integrins is an early event in migration promoted by the cell adhesion molecule L1. Experimental Cell Research 312:299-307.
• Demyanenko GP, Halberstadt A, and Maness PF. (2005) Neocortical Organization in Mice lacking cGMP-dependent Protein Kinase. Developmental Brain Research 160:1-8.
• Diestel S, Hinkle CL, Schmitz B, and Maness PF. (2005) NCAM140 stimulates integrin-dependent cell migration and is regulated by NCAM140 ectodomain shedding. Journal of Neurochemistry 95:1777-1784.
• Pillai-Nair N, Panicker AP, Rodriguiz RM, Miller K, Demyanenko GP, Huang J, Wetsel WP, and Maness PF. (2005) NCAM-Secreting Transgenic Mice Display Abnormalities in Interneurons and Behaviors Related to Schizophrenia. Neuroscience 25:4659-4671.
• Irintchev A, Koch M, Needham LK, Maness P, and Schachner M. (2004) Impairment of Sensorimotor Gating in Mice Deficient in Cell Adhesion Molecule L1 or its Close Homologue, CHL1. Brain Research 1029:131-134.
• Schmid RS, Kedar VP, Midkiff BR, and Maness PF. (2004) Adhesion Molecule L1 Stimulates Cell Migration through Vav2-Pak1 Signaling. Neuroreport 15:2791-2794.
• Grove M, Demyanenko G, Zipfel PA, Echarri A, Quiroz ME, Rodriquiz RM, Playford M, Martensen SA, Robinson MR, Wetsel WC, Maness PF, and Pendergast AM. (2004) Abi2-deficient mice exhibit defective cell migration, aberrant spine morphogenesis and deficits in learning and memory. Molecular and Cellular Biology 24:10905-10922.
• Demyanenko GP, Schachner M, Anton E, Schmid R-S, Feng G, Sanes J, and Maness P.F. (2004) Close Homolog of L1 (CHL1) Modulates Area-specific Neuronal Positioning and Dendrite Orientation in the Cerebral Cortex. Neuron 44:423-437
• Buhusi M, Midkiff BR, Gates AM, Richter M, Schachner M, and Maness PF. (2003) Close Homolog of L1 (CHL1) is an enhancer of integrin-mediated cell migration. Journal of Biological Chemistry 278: 25024-25031.
• Demyanenko GP and Maness PF. (2003) The L1 cell adhesion molecule is essential for topographic mapping of retinal axons. Journal of Neuroscience 23: 530-538.
• Otey CA, Boukhelifa M, and Maness PF. (2003) B35 Neuroblastoma Cells: An Easily Transfected Culture Cell Model of CNS Neurons. Methods in Cell Biology 71: 287-304.
• Thelen K, Kedar V, Schmid RS, Midkiff BR, and Maness PF. (2002) L1 potentiates integrin-dependent migration to extracellular matrix through endocytosis. Journal of Neuroscience 15:4918-4931.
• Liu R-Y, Schmid R-S, Snider WD, Maness PF. (2002) NGF enhances sensory axon growth induced by laminin but not by the L1 cell adhesion molecule. Molecular and Cellular Neuroscience 20:2-12.
• Needham LK, Thelen K, Schmid RS, and Maness PF. (2001) Cytoplasmic domain mutations of L1 associated with CRASH syndrome reduce L1-ankyrin interaction. Journal of Neuroscience 21:1490-1500.
• Demyanenko GP, Shibata Y, and Maness PF. (2001) Altered distribution of dopaminergic neurons in the brain of L1 null mice. Developmental Brain Research 126:21-30.
• Bliss T, Errington ME, Fransen E, Godfrained JM, Kauer J, Kooy F, Maness P, and Furley AJ. (2001) Long term potentiation in mice without L1-CAM. Current Biology 10:1607-1610.
• Schmid RS, Pruitt WM, and Maness PF. (2000) A MAP kinase signaling pathway mediates neurite outgrowth on L1 and requires SRC-dependent endocytosis. Journal of Neuroscience 20:4177-4188.
• Demyanenko GP, Tsai AY, and Maness PF. (1999) Abnormalities in Neuronal Process Extension, Hippocampal Development, and the Ventricular System of L1 Knockout Mice. Journal of Neuroscience 19:4907-4920.
• Schmid RS, Graff RD, Schaller MD, Chen S, Schachner M, Hemperly JJ, and Maness PF. (1999) NCAM stimulates the Ras-MAPK pathway and CREB phosphorylation in neuronal cells. Journal of Neurobiology 38:542-558.
• Fiordalisi JJ and Maness PF. (1999) Rek, an Axl/Tyro 3-related receptor-class tyrosine kinase, is expressed in Müller glia and differentiating neural subpopulations in the avian retina. Expimental Eye Research 68:201-210
• Morse WR, Whitesides III JG, LaMantia AS, and Maness PF. (1998) pp60c-src and p59fyn modulate axon guidance in the developing mouse olfactory pathway. Journal of Neurobiology 36:53-63.
• Beggs HE, Baragona SC, Hemperly JJ, and Maness PF. (1997) NCAM 140 Selectively Interacts with the Nonreceptor Tyrosine Kinases p59fyn and p125fak. Journal of Biological Chemistry 272:8310-8319.
• Biscardi JS, Denhez F, Buehler GF, Chesnutt DA, Baragona SC, O'Bryan J, Fults DW, and Maness PF. (1996) Rek, A Gene Expressed In Retina and Brain, Encodes a Novel Receptor Tyrosine Kinase of the Axl/Tyro 3 Family. Journal of Biological Chemistry 271:29049-29059.
• Klinz SG, Schachner M, and Maness PF. (1995) L1 and NCAM Antibodies Trigger Protein Phosphatase Activity in Growth Cone-enriched Membranes. Journal of Neurochemistry 65:84-95.
• Beggs HE, Soriano P, and Maness PF. (1994) Inhibition of NCAM-dependent Neurite Outgrowth in Fyn-minus Neurons. Journal of Cell Biology 127:825-833.
• Ignelzi MA, Miller DR, Soriano P, and Maness PF. (1994) Impaired Neurite Outgrowth of Src-minus Neurons on the Cell Adhesion Molecule L1. Neuron 12:873-884.
• Bare DJ, Wilkie MB, Lauder JM, and Maness PF. (1993) p59fyn In Rat Brain is Localized in Developing Axonal Tracts and Subpopulations of Adult Neurons and Glia. Oncogene 8:1429-1436.
• lgnelzi MA, Padilla SS, Warder DE, and Maness PF. (1992) Altered Expression of pp60c-src Induced by Peripheral Nerve Injury. Journal Comparative Neurololgy 315:171-177.
• Atashi JR, Klinz SG, Ingraham CA, Matten WT, Schachner M, and Maness PF. (1992) The L1 Neural Cell Adhesion Molecule Modulates Tyrosine Phosphorylation of Tubulin in Nerve Growth Cone Membranes. Neuron 8:831-842.